best peptides for sleep
Recommended Products

5 Best Peptides For Sleep For 2023

Sleep is instrumental to all forms of health, and it’s suggested that the typical adult get 6 to 9 hours of sleep per day.

As a result, you cannot receive full body wellness (body, soul, mind) without relying on steady sleep patterns.

There are many “solutions” that promise to remedy the common problem of not getting enough sleep each night.

One of those solutions are called peptides.

There are peptides designed for improving sleep habits, without adverse or otherwise harmful side effects.

There’s also evidence to suggest peptides can treat obesity and heart disease.1

Be that as it may, for now, let’s focus on how peptides influence sleep habits and can potentially help you get a better nights rest.

IMPORTANT: The below peptides are NOT intended for those under the age of 18. If you are under the age of 18, do NOT consider taking them under any circumstances whatsoever.

What are the 5 Best Peptides for Sleep?

Energy is a very broad concept of the human body.

There are medical experts that will have trouble giving you a standard definition.

For example, some energy in relation to your physical health and ability to complete tasks.

Meanwhile, others connect energy to cognitive functions like poor focus or memory.

As a result, peptides serve a broad purpose yet their full relation to improving sleep habits is still unknown.

The initial research on peptides is promising yet many of these substances remain outside FDA regulation.

Consequently, peptides are largely utilized for experimental purposes yet the ability to treat sleep disorders is encouraging.

Nevertheless, individuals suffering from poor sleep trends may want to turn to these noteworthy peptides for a solution:

  1. Epitalon
  2. CJC-1295 Peptide
  3. Ipamorelin
  4. Sermorelin
  5. AOD 9604 Peptide

Learn more about each of the 5 Best Peptides for Sleep, below:

#1. Epitalon

epitalon is the perfect peptide for sleep

Epitalon is notorious for its anti-aging properties.

Thus, the peptide is often considered a fountain of youth for senior citizens.

Moreover, Epitalon can deliver immediate benefits to reverse the awful trends of aging before they even begin.

For this reason, more medical experts are advocating for the use of peptides as a legitimate form of anti-aging treatment.2

Those that supplement Epitalon generally note deeper sleep patterns because of the peptide.

The peptide is an effective healing aid so much of its work needs to occur over time while you are fast asleep.3

It’s led to some utilizing Epitalon as a healing agent to improve the recovery time for a serious injury.4

Despite it, the FDA has yet to recognize Epitalon as an approved substance.

Click Here to pick up Epitalon from our #1 rated source, Core Peptides.

#2. CJC 1295

cjc 1295 peptide for sleep

CJC 1295 is easily among the best peptides for sleep improvements leading to better focus and energy.

Often, when patients suffer from low energy they are referencing strength, power, and endurance.

Notwithstanding, it fails to recognize that low energy is also attributed to poor mental and emotional health.

Patients traditionally report not feeling alert and constantly tired.

For this reason, how can you get physically stronger when you constantly feel exhausted?

CJC 1295 seeks to knock out several birds with one stone by targeting a vast array of conditions.5

For starters, CJC 1295 is reliable at gaining lean muscle for muscle growth/development.

Secondly, the peptide has also demonstrated impressive results in terms of weight loss.6

Finally, overall quality of life is improved largely due to better sleep habits.

Click Here to pick up CJC-1295 from our #1 rated source, Core Peptides.

#3. Ipamorelin

ipamorelin is a great peptide to improve sleep quality

Ipamorelin is a popular peptide that treats a series of conditions including poor sleep.

First and foremost, the peptide seeks to boost your immune system.

Unfortunately, it’s difficult for immune health to improve without the necessary time to rest.

Thus, if you suffer from poor sleep you likely also notice the side effects during the day.

Ipamorelin provides much-needed relief to your immune system via cellular rejuvenation.7

Moreover, patients report that recovery time is improved from wounds and injury.

Finally, Ipamorelin promotes lean muscle growth and overall strength.

These benefits lead many to consider Ipamorelin a trustworthy anti-aging treatment.

Click Here to pick up Ipamorelin from our #1 rated source, Core Peptides.

#4. Sermorelin

peptides for sleep

Sermorelin is a peptide designed to use at night.

Growth hormone (GH) secretion generally occurs at the highest levels while you sleep.

Thus, peptides like Sermorelin do the most positive work while you are drifting off into another realm.

Sermorelin recognizes the value of improving sleep habits as a primary method for improving overall health.8

The peptide (like many others on the list) is versatile and expedites healing and recovery.9

Sermorelin increases growth hormone-releasing hormone (GHRH) which leads to the peptide also being linked to weight management.10

Click Here to pick up Sermorelin from our #1 rated source, Core Peptides.

#5. AOD 9604 Peptide

aod 9604 is the perfect peptide for improved sleep

There are many reasons to consider AOD 9604 especially if you are also trying to lose weight.

AOD 9604 was specifically designed as an anti-obesity drug yet offers other benefits.

The peptide is a modified fragment of the human growth hormone (HGH) and influences the pituitary gland (brain).11

Consequently, the peptide is also connected to treating a variety of mental and cognitive issues such as poor sleep.

AOD 9604 restores your metabolism and makes several other bodily repairs which are most effective at night, when you are sleeping (not awake!).12

The peptide may also assist in bone and cartilage repair.

What’s more, AOD 9604 peptide reduces hunger cravings while producing minimal side effects.

Click Here to pick up AOD 9604 from our #1 rated source, Core Peptides.

Frequently Asked Questions

Here are some frequently asked questions OMK receives about tracking down the top peptides for improving sleep quality:

Do Peptides Improve Sleep Quality?

Peptides are versatile compounds that link to amino acids and replicate several functions of proteins.

For this reason, peptides have been linked to weight loss and building lean muscle, as well as improved sleep habits.

In general, humans sleep less at night as they age due to hormonal deficiencies.

Often, these hormonal imbalances are attributed to growth hormone (GH) and melatonin.13

The latter has especially received a lot of attention more recently in terms of treating sleeping deficiencies.

How Do They Work?

Peptides are known to influence hormones like GH and melatonin as well as many others.

Peptides have been especially effective increasing GH levels.

Research notes that the growth hormone spends more time in your sleep’s delta wave stage.14

It’s important to note that the body endures different levels of healing and regeneration depending on the stage of sleep.

Accordingly, many consider the delta stage arguably the most crucial stage in your sleep patterns.

The delta stage contributes to high volumes of GH secretion, muscle hypertrophy, and neurogenesis.

In other words, think of the delta stage as the “deep sleep state” where your body receives the most regenerative healing.

Do Peptides affect melatonin?

Melatonin is connected to a variety of improvements in sleep including quality and duration.

Melatonin helps target low energy which is a common problem linked to aging.

Furthermore, it may influence other physical factors such as strength, power, stamina, and endurance.

What are the best types of peptides for treating poor sleep?

What’s incredible about peptides that improve sleeping habits is how you can receive treatment from a wide range of options.

Peptides influence the body at the cellular, hormonal, mental, and sexual levels.

Subsequently, improved sleep is a common positive reaction from peptides regardless of which one you seek out.

For example, those seeking to improve stamina and endurance may want to focus on buying peptides that promote cellular energy.

Meanwhile, a man suffering from low strength, power, or libido would want to shop for peptides that promote hormonal energy.

Regardless, a common positive effect of peptide use is improved sleep.


Sleeplessness and insomnia rates are increasing in the United States.

There are many factors that influence restlessness such as anxiety, stress, and trauma.

Meanwhile, poor sleep may be due to chronic pain or another medical issue that prevents a solid night’s rest.

Furthermore, poor sleep is sometimes the result of alcohol/drug abuse, sleep apnea, restless leg syndrome, or grief.

Thus, factors outside your control may influence sleep tendencies along with lifestyle choices.

You can make better choices in terms of diet, exercise, and levels of consumption.

Regardless, sometimes a lack of quality sleep is nothing more than getting older and hormonal imbalances.

In the past, this issue was unavoidable yet there is a new hope to treat sleep conditions with peptides.

As a result, rely on these 5 Best Peptides for Sleep:

  • Epitalon
  • CJC 1295
  • Ipamorelin
  • Sermorelin
  • AOD 9604 Peptide


  1. Gao Y, Yuan X, Zhu Z, Wang D, Liu Q, Gu W. Research and prospect of peptides for use in obesity treatment (Review). Exp Ther Med. 2020;20(6):234. doi:10.3892/etm.2020.9364 (source)
  2. Wang J, Wu Y, Chen Z, Chen Y, Lin Q, Liang Y. Exogenous Bioactive Peptides Have a Potential Therapeutic Role in Delaying Aging in Rodent Models. Int J Mol Sci. 2022;23(3):1421. Published 2022 Jan 26. doi:10.3390/ijms23031421 (source)
  3. Anisimov VN, Khavinson VKh, Popovich IG, et al. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. 2003;4(4):193-202. doi:10.1023/a:1025114230714 (source)
  4. Kossoy G, Zandbank J, Tendler E, et al. Epitalon and colon carcinogenesis in rats: proliferative activity and apoptosis in colon tumors and mucosa. Int J Mol Med. 2003;12(4):473-477. (source)
  5. Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. doi:10.1210/jc.2005-1536 (source)
  6. Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ. Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Horm IGF Res. 2009;19(6):471-477. doi:10.1016/j.ghir.2009.03.001 (source)
  7. Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-561. doi:10.1530/eje.0.1390552 (source)
  8. Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?. Clin Interv Aging. 2006;1(4):307-308. doi:10.2147/ciia.2006.1.4.307 (source)
  9. Prakash A, Goa KL. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 1999;12(2):139-157. doi:10.2165/00063030-199912020-00007 (source)
  10. Sinha DK, Balasubramanian A, Tatem AJ, et al. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020;9(Suppl 2):S149-S159. doi:10.21037/tau.2019.11.30 (source)
  11. Ng FM, Sun J, Sharma L, Libinaka R, Jiang WJ, Gianello R. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Horm Res. 2000;53(6):274-278. doi:10.1159/000053183 (source)
  12. Cox HD, Smeal SJ, Hughes CM, Cox JE, Eichner D. Detection and in vitro metabolism of AOD9604. Drug Test Anal. 2015;7(1):31-38. doi:10.1002/dta.1715 (source)
  13. Zisapel N. New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation. Br J Pharmacol. 2018;175(16):3190-3199. doi:10.1111/bph.14116 (source)
  14. Van Cauter E, Plat L. Physiology of growth hormone secretion during sleep. J Pediatr. 1996;128(5 Pt 2):S32-S37. doi:10.1016/s0022-3476(96)70008-2 (source)

See Also

Best Peptides for Weight Loss & Fat Burning

Best Peptides For Hair Growth

Best Peptide Sources & Companies

Rob V.
Peptides For Sleep

Peptides For Sleep

4.7 out of 5 (55 Ratings)

The best peptides for sleep improve duration and quality of your night's rest. You'll appreciate a wide range of benefits from peptides.
Affiliate Disclosure: This post may contain affiliate links. If you click and purchase, I may receive a small commission at no extra cost to you. I only recommend products I have personally vetted. Learn more.

Leave a Reply

Your email address will not be published. Required fields are marked *