Peptides for weight loss offer a wealth of potential.
These peptides offer rapid fat-burning assistance without disrupting other functions of the body.
As a result, you’ll reach weight loss goals in a far healthier manner compared to performance-enhancing supplements.
Meanwhile, you’ll also appreciate the other benefits of peptides including the stimulation of lean muscle.
Peptides also feature a variety of anti-aging properties for men concerned about looking and feeling “older”.
Learn more about the 6 Best Peptides for Weight Loss in our complete review of the top products for 2022.
Table of Contents
Peptides for Weight Loss
It’s important to keep in mind that using peptides for weight loss is not a brand new concept.
Nevertheless, peptides have received a lot more mainstream attention over the last few years leading to a lot of misconceptions.
For starters, there is plenty of medical research and clinical trials to support the use of peptides for losing weight.
Peptides effectively burn fat and increase lean muscle without disrupting other natural processes in the body.
Furthermore, peptides are effective at maintaining weight loss without demanding a strict diet or workout regime.
Are you seeking rapid weight loss improved energy, and new muscle growth?
Men (and even women) should consider these 6 Best Peptides for Weight Loss in 2022:
- AOD 9604
- Tesamorelin
- CJC 1295
- Ipamorelin
- GHRP-6
- 5-Amino-1MQ
Now, let’s examine each peptide for weight loss in more detail:
#1. AOD 9604
Note: Click Here to pick up AOD 9604 from our #1 rated source, Core Peptides.
The debate over the best peptide for weight loss remains crowded since the compounds remain in experimental stages.
Nonetheless, peptides have an incredible potential to influence weight loss.
Studies indicate that AOD 9604 is a fragment derivative of Growth Hormone (GH).1
Moreover, AOD 9604 promotes lipolysis as well as inhibits lipogenesis.2 3
Third, AOD 9604 peptide utilizes body fat reserves to prevent the accumulation of excess fat.
Ultimately, you can reach the desired weight and maintain it, long-term.
It’s definitely worth noting that AOD 9604 is one of the few peptides that has received approval from the FDA.
AOD 9604 offers several benefits such as:
- Stimulates Fat Cell Release
- Reduces Body Fat (Lipolysis)
- Repairs Cartilage & Bone Damage
What’s also impressive is the rapid results.
AOD 9604 is considered one of the most effective peptides available with studies revealing as much as a 50% reduction in weight gain.4
The results were also fast as users reported weight drops in just over 3 weeks with impressive results arriving in less than 12 weeks.
Studies in animals support what has been shown with humans in terms of reducing body weight, increasing fat oxidation, and increasing lipolysis.5
More so, AOD 9604 can produce more significant weight loss (and in a shorter time frame) than diet and exercise alone.
Notwithstanding, there are lifestyle choices and genetic factors that influence metabolism for the better or worse.
Thus, it’s still advised with any peptide designed for weight loss to also implement regular exercise and healthy eating habits.
Regardless, AOD 9604 is widely deemed one of the safest and most effective peptides you can take for losing weight.
Click Here to pick up AOD 9604 from our #1 rated source, Core Peptides.
#2. Tesamorelin
Note: Click Here to pick up Tesamorelin from our #1 rated source, Core Peptides.
Tesamorelin is a wonderful peptide that has already proven effective at treating HIV-associated lipodystrophy.
Still, there is even more hope for Tesamorelin to revolutionize weight management, too.
Clinical trials indicate that Tesamorelin peptide does cut down on visceral adipose tissue (fat tissue), especially in the abdomen.6
Tesamorelin is a growth hormone-releasing hormone analog that is known to increase IGF-1 levels in both men and women.7
The peptide is effective at treating weight loss yet also promises to deliver improvements in cognitive function and mental health.
There is even research dedicated to finding a link between Tesamorelin and treating Alzheimer’s disease.8
Tesamorelin was previously marked under the name Egrifta to combat excess abdominal fat.
While the peptide has been effective at targeting stomach fat it remains outside the regulation of the FDA.
For this reason, Tesamorelin is only available online despite its success in helping many achieve the weight they desire.
Click Here to pick up Tesamorelin from our #1 rated source, Core Peptides.
#3. CJC 1295
Note: Click Here to pick up CJC 1295 from our #1 rated source, Core Peptides.
CJC 1295 is considered one of the best peptides for weight loss.
The synthetic peptide is designed to stimulate the release of growth hormone (GH) and Insulin-like Growth Factor 1 (IGF-1).9
Consequently, the peptide acts on target cells that harbor adipocytes (fat cells).10
Thus, CJC 1295 is notorious for promoting fat breakdown and expediting weight loss as a result.
More noteworthy, CJC 1295 is especially potent for weight loss when stacked with Ipamorelin (more information, below).
Ipamorelin is another powerful growth hormone secretagogue.11
The two are versatile peptides that can burn fat while also stimulating new muscle growth.
CJC 1295 has anti-aging properties that are currently undergoing more clinical research.
Additionally, it’s worth noting that CJC 1295 is generally paired together with a Drug Affinity Complex (DAC).
CJC 1295 is not typically a long-acting GHRH (growth hormone stimulating hormone) without the addition of DAC.
Nevertheless, versions of CJC 1295 are available with or without DAC.
Those considering CJC 1295 should do their homework because the peptide does carry some risks.
Peptides are still designed for experimental use and research purposes.
Therefore, speak with a physician before starting any new supplement, especially if you take other prescription medication(s).
Click Here to pick up CJC 1295 from our #1 rated source, Core Peptides.
#4. Ipamorelin
Note: Click Here to pick up Ipamorelin from our #1 rated source, Core Peptides.
Ipamorelin, as previously noted, is comparable to CJC 1295.12
It’s a growth hormone secretagogue that assists in the production of endogenous growth hormone.
However, Ipamorelin targets a different receptor (ghrelin) in the pituitary gland which subsequently contributes to a higher rate of growth hormone production.13
As a result, those that supplement Ipamorelin (individually or combined in a stack with CJC 1295) note rapid weight loss.
Moreover, Ipamorelin is effective at helping replace fat with lean muscle.
Those that cycle Ipamorelin and CJC 1295 notice a prolonged improvement in hGH production.14
The result is vast improvements in overall health including improved sleep, energy, focus, and recovery.
Ipamorelin does not feature a long list of dangerous side effects.
Those that supplement suggest starting with a short cycle (less than 3 months) and monitoring your metabolism throughout the process.
Click Here to pick up Ipamorelin from our #1 rated source, Core Peptides.
#5. GHRP-6
Note: Click Here to pick up GHRP-6 from our #1 rated source, Core Peptides.
Growth Hormone-Releasing Hexapeptide – or GHRP-6 – is another one of the best peptides for weight loss.15
GHRP-6 features an impressive 28 amino acids which are higher than most peptides.
Thus, it classifies as an “HGH secretagogue” that is adept at burning fat and maintaining weight loss.16
GHRP-6 is noteworthy for increasing both growth hormone (GH) and Insulin-like Growth Factor (IGF-1).
Thus, athletes and bodybuilders have tapped into this wonderful peptide for decades.
However, GHRP-6 is just beginning to receive mainstream appeal for weight loss (like a lot of peptides that have been supplemented underground forever).
One reason GHRP-6 is becoming increasingly popular is that it enhances appetite.
Thus, you can still enjoy food, eat a reasonable nutrition plan, and still get enough calories to burn fat and gain lean muscle.
Finally, there is optimism that GHRP-6 is another potential anti-aging treatment.17
Click Here to pick up GHRP-6 from our #1 rated source, Core Peptides.
#6. 5-Amino-1MQ
Note: Click Here to pick up Amino-1MQ from our #1 rated source, Swiss Chems.
Amino-1MQ is a thriving anti-obesity drug and has slipped under the radars of some experts.
The drug inhibits an enzyme in cells which speeds up the fat metabolism.
Moreover, Amino-1MQ is successful at reducing blood cholesterol levels.
Amino-1MQ is a relatively new discovery in the medical community and technically not a peptide.
However, Amino-1MQ functions like a peptide since it easily crosses cell membranes and demonstrates many of the same properties.
Amino-1MQ is known as a selective membrane-permeable molecule that blocks the NNMT enzyme (as well as works on mitochondria).
Consequently, users that take the drug witness improvements in energy and endurance.
Additionally, the peptide has the potential to reverse diet-induced obesity as well as treat type II diabetes.
The substance is best supplemented when stacked along with an NAD+ or NAD+ precursor.
Click Here to pick up Amino-1MQ from our #1 rated source, Swiss Chems.
Frequently Asked Questions
It’s natural to have questions or concerns about peptides.
Peptides for weight loss are safe and reliable but require some special care and knowledge to utilize properly.
Here are some frequently asked questions:
What are Peptides?
Peptides exist in the body for several reasons.
In modern science, new research and technology have contributed to incredible discoveries.
In turn, researchers are finding effective methods to develop safe alternatives that actually produce results.
Consequently, synthetic peptides have transformed into a popular type of injection for those seeking a complete body overhaul.
Peptides are designed for weight loss as well as for building lean muscle.
They also produce a plethora of other benefits:
- Rapid Weight Loss
- Muscle Growth
- Increased Strength
- Increased Energy
- Faster Recovery & Healing
Those that supplement peptides notice improved overall athletic performance.
The bottom line: you have more energy, feel better, and recover quicker from injury or intense exercise.
Despite it all, peptide use remains controversial in fitness and bodybuilding because the compounds are not thoroughly researched.
The FDA has been dragging its feet on peptides for years despite largely supportive clinical research advocating their use for a variety of conditions.
In consequence, those that are curious about trying peptides need to resort to an online marketplace they are not sure they can trust.
How do peptides work?
Peptides are tiny varieties of proteins.
It’s essentially a string of amino acids that range in function and benefit.
Thus, you can truly say that no 2 peptides are created the same.
Peptides exist naturally in the body and stimulate a ton of natural processes.
Modern science is attempting to stimulate weight loss and muscle growth by utilizing synthetic versions.
Furthermore, peptides have a wealth of potential for treating skin conditions, flexibility, and bone density.
The ability to heal from injuries and recover sooner also contributes to the anti-aging properties of peptides.
You can get the most from weight loss goals by using supplements designed to burn fat, build lean muscle, and moderate cravings.
Building a stack designed to cut weight is the premiere method for producing rapid weight loss.
How do you take peptides?
Peptides are available in powder (lyophilized) and capsule form.
Meanwhile, others prefer to administer the substance via an injection.
The general notion is that peptides absorb the best in the bloodstream and therefore require injections.
While not exactly true there are advantages to utilizing injections for rapid absorption.
Nonetheless, peptides are available in a variety of formats depending on personal preference.
It’s crucial to shop from a trustworthy source that third-party tests its peptides for consistency and purity.
Peptide injections do require some preparation.
You’ll need to mix the powder into a vial with water to “reconstitute” the substance.
Peptides are usually safe to store in a refrigerator under proper temperatures for 1-3 months.
The dosage guidelines and the number of injections depend on a variety of factors.
Are peptides safe?
Yes, peptides are generally safe for consumption.
The FDA has already approved AOD 9604 and Semaglutide for weight loss.
Meanwhile, other peptides for weight loss like Tesofensine are currently receiving phase 3 trials.
Consequently, it feels like only a matter of time before more Americans realize the incredible potential of peptides.
Obesity is a serious threat to public health in the United States as well as the leading cause of preventable death.
Peptides can offset the devastating trends in a safe and effective manner.
They are designed to mimic the action of naturally occurring peptides leading to impressive weight loss results.
Peptides are not steroids or performance-enhancing drugs.
More importantly, they do not carry the same serious and dangerous side effects as anabolic steroids.
Be that as it may, new users should consider speaking with a physician before starting any new supplement or weight stack.
What are the side effects of peptides?
The side effects of peptides for weight loss are not considered common or severe.
The most common side effects are fatigue or numbness in the hands and feet.
Water retention is also possible with peptides which is why short cycles are suggested for first-time users.
Even more, Post Cycle Therapy (PCT) is sometimes advised for certain peptides.
Lastly, injections are known to produce minor irritation and discomfort around the site of injection.
Conclusion
Peptides for weight loss are already changing personal lives.
Now, it’s a matter of how long before it alters the world.
Peptides are starting to receive mainstream attraction.
Nonetheless, only a few peptides are approved by the FDA for consumption (AOD 9604, Semaglutide).
Thus, you’ll need to rely on reputable suppliers to buy safe and reliable solutions.
Peptides selectively target fat burning as opposed to previous weight loss strategies aimed at depriving people of nutrients (diets) and excess calorie burning.
Peptides for weight loss produce noticeable results in 3-6 months with the right method of intake, dosage, exercise, and nutrition plan.
References
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Heffernan M, Summers RJ, Thorburn A, et al. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. Endocrinology. 2001;142(12):5182-5189. doi:10.1210/endo.142.12.8522 (source)
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Lass A, Zimmermann R, Oberer M, Zechner R. Lipolysis – a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog Lipid Res. 2011;50(1):14-27. doi:10.1016/j.plipres.2010.10.004 (source)
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Batchuluun B, Pinkosky SL, Steinberg GR. Lipogenesis inhibitors: therapeutic opportunities and challenges. Nat Rev Drug Discov. 2022;21(4):283-305. doi:10.1038/s41573-021-00367-2 (source)
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Wilding J. AOD-9604 Metabolic. Curr Opin Investig Drugs. 2004;5(4):436-440. (source)
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Heffernan MA, Thorburn AW, Fam B, et al. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. Int J Obes Relat Metab Disord. 2001;25(10):1442-1449. doi:10.1038/sj.ijo.0801740 (source)
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Falutz J, Mamputu JC, Potvin D, et al. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data. J Clin Endocrinol Metab. 2010;95(9):4291-4304. doi:10.1210/jc.2010-0490 (source)
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Alehagen U, Johansson P, Aaseth J, Alexander J, Brismar K. Increase in insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 1 after supplementation with selenium and coenzyme Q10. A prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens. PLoS One. 2017;12(6):e0178614. Published 2017 Jun 13. doi:10.1371/journal.pone.0178614 (source)
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Froestl W, Pfeifer A, Muhs A. Cognitive enhancers (nootropics). Part 3: drugs interacting with targets other than receptors or enzymes. disease-modifying drugs. J Alzheimers Dis. 2013;34(1):1-114. doi:10.3233/JAD-121729 (source)
- Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. doi:10.1210/jc.2005-1536 (source)
- Blaszczak AM, Jalilvand A, Hsueh WA. Adipocytes, Innate Immunity and Obesity: A Mini-Review. Front Immunol. 2021;12:650768. Published 2021 Jun 24. doi:10.3389/fimmu.2021.650768 (source)
- Sigalos JT, Pastuszak AW. The Safety and Efficacy of Growth Hormone Secretagogues. Sex Med Rev. 2018;6(1):45-53. doi:10.1016/j.sxmr.2017.02.004 (source)
- Johansen PB, Nowak J, Skjaerbaek C, et al. Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Horm IGF Res. 1999;9(2):106-113. doi:10.1054/ghir.1999.9998 (source)
- Pradhan G, Samson SL, Sun Y. Ghrelin: much more than a hunger hormone. Curr Opin Clin Nutr Metab Care. 2013;16(6):619-624. doi:10.1097/MCO.0b013e328365b9be (source)
- Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C. Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus. J Exp Pharmacol. 2012;4:149-155. Published 2012 Oct 19. doi:10.2147/JEP.S35396 (source)
- Bowers CY, Sartor AO, Reynolds GA, Badger TM. On the actions of the growth hormone-releasing hexapeptide, GHRP. Endocrinology. 1991;128(4):2027-2035. doi:10.1210/endo-128-4-2027 (source)
- Aghdam Shahryar, Habib & Lotfi, Alireza. (2016). Effects of peripheral administration of ghrelin antagonist [D-Lys3]-GHRP-6 on growth performance and blood biochemical indices in broiler chickens. Archives Animal Breeding. 59. 113-119. 10.5194/aab-59-113-2016. (source)
- Bartke A. Growth hormone and aging: a challenging controversy. Clin Interv Aging. 2008;3(4):659-665. doi:10.2147/cia.s3697 (source)
See Also
Best Peptide Sources / Companies
Born and raised in Woodbridge, NJ, he graduated from the New Jersey Institute Of Technology with an MBA in eCommerce.His hobbies include beach volleyball, target shooting, and lifting.
Rob is also a Commercially rated pilot and Certified Flight Instructor (CFI), with over 1,500 hours of flight time.
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