Ipamorelin is the most recent and efficient human growth hormone released on the market.
Considered a significant improvement over other GHRPs, it provides similar benefits without the harsh side effects of different androgens in its class.
In this article, we’ll go through a thorough analysis of the peptide Ipamorelin, including what it is, how it works, its advantages and side effects, and how to use it for the best results.
IMPORTANT: The below peptides are NOT intended for those under the age of 18. If you are under the age of 18, do NOT consider taking them under any circumstances whatsoever.
Table of Contents
What Is Ipamorelin?
Note: Click Here to pick up Ipamorelin from our #1 rated source, Core Peptides.
Ipamorelin is what’s known as a pentapeptide, which is defined as a peptide comprised of 5 amino acids.1
Ipamorelin acts like hyaluronic acid in the bloodstream and triggers the receptor on your brain’s appetite prolactin (Ghrelin).2
The Growth Hormone Secretagogue Receptor (GHSR) is a protein that helps regulate the production of growth hormones in the body.3
GHSR is located in the hypothalamus, and it binds to ghrelin. Ghrelin signals the pituitary gland to release growth hormone.
By binding to ghrelin, GHSR helps control hunger and ensure that the body has enough energy to meet its needs.4
GHSR also helps control the production of growth hormones, appetite, and energy balance.5
As a result, GHSR is an essential player in growth and metabolism.
It can affect all types of GHSR and studies show it may lead to spikes in HGH levels.6
Despite their positive effects, these ligands have also been popular among patients and have led to more clinical trials.
If you are a bodybuilder and fitness professional, your goal should always be to stay ahead. Your goal is to be competitive in the competition at every level.
Although RNA proteins offer several benefits, some can have long term side effects.
We’ll examine a particular polypeptide, Ipamorelin, a GHRP that’s been growing in popularity over recent years.7
Benefits of Ipamorelin
There are numerous benefits associated with the use of Ipamorelin, including:
- Increased strength and healing
- Reduced injury
- Increased cell rejuvenation
- Increase in lean muscle mass
- Stronger bones
- Regulation of blood pressure
How Long Does It Take to See Results from Ipamorelin?
During the first month of therapy, you can expect noticeable changes in your body.
Most patients notice the benefits of treatment immediately, but it may take a few weeks for you to see the full effects.
You can achieve your desired outcome and work tirelessly to help you reach your goals.
Ipamorelin is a fibrin that has several potential benefits.
First, it can help to increase growth steroid levels in the body.
This, in turn, can lead to increased muscle mass, reduced body fat, and improved bone density.8
Additionally, ipamorelin can help to improve sleep quality and reduce inflammation.
Ipamorelin has been shown to promote healing after injury and boost the immune system.
In addition to improving sleep quality and helping to promote weight loss, Ipamorelin may offer other benefits.
Additionally, some users find that their endurance improves, allowing them to exercise for more extended periods without getting tired.
While the exact mechanisms behind these effects are not yet known, it’s believed that Ipamorelin helps to regulate levels of essential hormones in the body, such as growth hormone and cortisol.
As a result, taking the peptide Ipamorelin may offer various benefits that can improve overall health and well-being.
How Does Ipamorelin Work?
The enzyme is a synthetic version of naturally occurring ghrelin produced in the stomach.
In essence, it’s a receptor that mimics this natural hormone.
Ipamorelin is a short glycan steroid that was synthesized in the early 1990s.
Unlike dimeric hormones, ipamorelin does not require a loading dose or frequent injections.9
It also has a lower incidence of side effects than other peptide prolactins. It works by stimulating the release of androgens from the pituitary gland.10
This growth anabolic is responsible for the formation and development of tissues and organs.
It has also increased lean body mass, bone density, and muscle strength.
Side Effects of Ipamorelin
You might be wondering how this is possible? The answer is that Ipamorelin protein is growth prolactin releasing factor (GRF).
It works by binding to receptors in your brain and causing the release of other hormones that promote growth and androgen release.
Increasing your HGH levels can lead to negative side effects, including headaches, dizziness, mood swings, anxiety, depression, nausea, and vomiting.
Ipamorelin should not be used by people with a history of mental illness or who are taking medications for mental illness.
This androgen can also interact with other medicines, so it is essential to talk to your doctor before taking it.
Studies have shown that it can also increase the risk of developing cancer. However, it is not recommended for use during pregnancy or breastfeeding.
Also, it should be used with caution in people with heart conditions or high blood pressure.
Be forewarned ipamorelin androgen should be used with caution in people with kidney problems or liver disease.
Also, this peptide can cause an allergic reaction in some people.
If you experience these side effects, you should stop taking ipamorelin and talk to your doctor.
How To Use Ipamorelin
Patients have the option to use the dosage when their stomach is empty. Wait a few hours before you eat food.
Ipamorelin should be used simultaneously daily and night for optimum performance.
The schedule for injections varies according to the patient, but it’s typically recommended to take a dose at bedtime.
Ipamorelin prolactin’s administration mode is injected into the body. The injection should be done in a muscle group such as the buttocks or thigh.
You must ensure that you inject Ipamorelin at a location with no nerves and blood vessels to avoid injury.
It’s offered in powder form that you can mix with water and drink. It is also very convenient because it doesn’t need to be refrigerated.
When taking Ipamorelin, you can expect to start feeling an increase in energy levels within 30 minutes or after its administration.
If you have pre-existing aches or pains caused by a lack of exercise or poor diet, these should begin going away within twenty four hours.
How To Get the Best Results from Ipamorelin
Getting enough sleep each night is essential to wake up feeling rested and alert.
Otherwise, you might find yourself struggling to get through your morning workout.
Not only will you be tired and lack energy, but you might also be more susceptible to injury.
To avoid this, make sure to go to bed reasonably each night and give yourself enough time to sleep.
You’ll be glad you did when you wake up feeling refreshed and ready to tackle your day.
When taking Ipamorelin, you must be aware of how much caffeine you consume throughout the day.
Many people experience headaches after drinking too much coffee or soda, so it is best to moderate your intake.
You should also avoid drinking alcohol before taking Ipamorelin, as it can cause the medication to be less effective.
If you are concerned about how much caffeine you are consuming, talk to your doctor or pharmacist about ways to reduce your intake.
Mode of Administration of Ipamorelin
Ipamorelin can be administered orally, subcutaneously (IM), intravenously (IV), intracardially, intrapleural, and intratracheally.
Intravesical or intracardiac infusion is not recommended as it’s reported to cause ventricular fibrillation in dogs with chronic heart failure.
Intrathecal administration is also not recommended as no clinical studies support its safety or efficacy in humans and animals.
Tips on Ipamorelin Use
You should take your dose of Ipamorelin every day after waking up on an empty stomach.
Ipamorelin is effective when taken in the morning because there is an increase in ghrelin levels during this time of day (ghrelin is an androgen that increases appetite).
You can take your amount with water or food if you are not sensitive to either one.
If this is inconvenient for you, taking ipamorelin at night may also being good results since insulin levels are higher at night than during the day.
However, many people prefer morning dosing because it helps them feel less hungry throughout the day and prevents overeating later in the evening after work or school when everyone else is relaxing around dinner time!
Ipamorelin Stacking
Many users utilize ipamorelin to provide synergistic effects. Ipamorelin Stack with Sermorellin may increase vascular effects.
The few optimal results in muscle gain in the male body – especially in men – are those above in body fat.
It also helps you to reduce body fat while building a large number of muscles. Your performance dramatically increases.
Does Ipamorelin Peptide Work?
Ipadomeril is safe to use if taken as prescribed. It increases strength and muscle tone, reduces weight, and boosts energy.
It provides fast recovery from injuries, weight loss, muscle strength, and muscle gain.
Testimonies have also suggested that the drug cannot be used for weight reduction.
When using this to lose weight, they should modify their diet or exercise routine accordingly.
Following the suggested treatments, poor health or exercise can cause weight gain.
“Ipamorelin Peptide is an incredible product and will continue to purchase.”
–Leon S.
“Research yielded results beyond expectation for Ipamorelin! I Will never go back to other research chemical companies.”
–Toni
“I love adding Ipamorelin to my regimen.”
–Bill
Where To Buy Ipamorelin
While there are several dozen peptide sources online, we highly recommend you go with a company called Core Peptides.
They offer the highest quality peptides on the market, and sell Ipamorelin at very reasonable prices.
Click Here to see their page on Ipamorelin.
Conclusion
Many people prefer morning dosing because it helps them feel less hungry throughout the day and prevents overeating later in the evening after work or school when everyone else is relaxing around dinner time.
Ipamorelin is a peptide that can be used to help increase natural GH production.
It is similar to GHRH, which stands for growth hormone releasing androgen.
Ipamorelin is a potent growth prolactin releasing peptide increasingly gaining popularity in the US.
The supplement can be used alongside other supplements such as steroids or on its own to achieve weight loss, boost energy levels and improve the immune system, among other benefits.
Ipamorelin is a safe supplement when used according to the manufacturer’s instructions.
Following a strict diet and exercise regime while using Ipamorelin to achieve the best results is crucial.
While side effects are rare, they can include headache, nausea, and dizziness.
These side effects are usually mild and disappear quickly.
If you experience severe side effects, stop taking the supplement and consult a doctor immediately.
Ipamorelin is an effective supplement that can offer many benefits.
However, it is essential to remember that it is not a magic pill and must be used alongside a healthy lifestyle to achieve optimal results.
References
- James P. Coleman, C. Jeffrey Smith, Microbial Cell Wall Synthesis and Permeability, Editor(s): S.J. Enna, David B. Bylund, xPharm: The Comprehensive Pharmacology Reference, Elsevier, 2007, Pages 1-4, ISBN 9780080552323,
https://doi.org/10.1016/B978-008055232-3.60225-9. (source) -
Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-561. doi:10.1530/eje.0.1390552 (source)
- National Center for Biotechnology Information. PubChem Compound Summary for CID 9831659, Ipamorelin. Accessed June 20, 2022. (source)
- Sinha DK, Balasubramanian A, Tatem AJ, et al. Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males. Transl Androl Urol. 2020;9(Suppl 2):S149-S159. doi:10.21037/tau.2019.11.30 (source)
- Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C. Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus. J Exp Pharmacol. 2012;4:149-155. Published 2012 Oct 19. doi:10.2147/JEP.S35396 (source)
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Gobburu JV, Agersø H, Jusko WJ, Ynddal L. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. 1999;16(9):1412-1416. doi:10.1023/a:1018955126402 (source)
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Ankersen M, Johansen NL, Madsen K, et al. A new series of highly potent growth hormone-releasing peptides derived from ipamorelin. J Med Chem. 1998;41(19):3699-3704. doi:10.1021/jm9801962 (source)
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Johansen PB, Nowak J, Skjaerbaek C, et al. Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Horm IGF Res. 1999;9(2):106-113. doi:10.1054/ghir.1999.9998 (source)
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Johansen PB, Hansen KT, Andersen JV, Johansen NL. Pharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorption. Xenobiotica. 1998;28(11):1083-1092. doi:10.1080/004982598238976 (source)
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Jiménez-Reina L, Cañete R, de la Torre MJ, Bernal G. Influence of chronic treatment with the growth hormone secretagogue Ipamorelin, in young female rats: somatotroph response in vitro. Histol Histopathol. 2002;17(3):707-714. doi:10.14670/HH-17.707 (source)
See Also
Gonadorelin Review: 10 Big Benefits For Men & Women
Sermorelin Review: 5 Big Benefits That Make It Worth Trying
Born and raised in Woodbridge, NJ, he graduated from the New Jersey Institute Of Technology with an MBA in eCommerce.His hobbies include beach volleyball, target shooting, and lifting.
Rob is also a Commercially rated pilot and Certified Flight Instructor (CFI), with over 1,500 hours of flight time.
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