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LGD 3303 Review (2023): Dosage, Results, Side Effects, & More

Many bodybuilders and other athletes are not happy with the results they are getting.

They don’t want to take anything illegal or that could cause serious and potentially deadly health issues, but they want to start seeing changes in their bodies.

Enter SARMs and LGD-3303.

IMPORTANT: The below research chemical is NOT intended for those under the age of 18.  If you are under the age of 18, do NOT consider taking it under any circumstances whatsoever.

Also, if you’re planning on joining the military, cease using this (and really any) compound at least a couple months before going to MEPS. 

They can cause a false positive on a drug test, and will affect your chances of joining!

What Is LGD-3303?

lgd3303 reviews benefits results

Note: Click Here to buy LGD-3303 legally online from our #1 rated source, Pure Rawz.

LGD-3303 is relatively new in the field of SARMs. Because it is so new, it means that there is not as much information about it as there are the other popular SARMs.

More testing and research will need to be done.

Many are saying that this SARM is one of the best options on the market today when it comes to getting the biggest mass and strength gains.

LGD-3303 is a selective androgen receptor modulator (SARM), which was originally developed as a means to help treat muscle wasting illnesses, as well as conditions like osteoporosis.1

It has been used by older individuals to help them maintain strength.

Naturally, this has gained the attention of many athletes and bodybuilders who want to know just how much this SARM could help them.

It has proven to be very effective at binding to the androgen receptor.

Once it binds, it can create anabolic effects in muscle and bone that are similar to the effects people have gained from using steroids.2

Simply put, it means increases in muscle size and strength.

How Exactly Does LGD-3303 Work?

LGD-3303 is a SARM that has good oral bioavailability and acts as a selective agonist for the androgen receptor and a full agonist for anabolic effects.3

It is considered to be one of the top SARMs available when it comes to strengthening bones and muscle mass.4

Some have compared it to anabolic steroids given the effectiveness it can offer without the drawbacks.

It is non-steroidal and is ingested orally, binding to the androgen receptor, ultimately allowing the muscles and bones to undergo an anabolic effect.5

Muscles grow and become stronger without causing you to retain a lot of water. This means you can gain size without feeling too thick and bloated.

Detailed Benefits of LGD 3303

SARMs have become very popular in the last several years and with good reason.

When taken correctly, they do have the capability to provide some great effects and it’s considered one of the strongest SARMs.

Let’s look at some of the benefits that users have talked about with LGD-3303.

#1. LGD 3303 Decreases Water Retention

It is known for being able to provide muscular fullness even though it is a dry compound.

Of course, because there is so little research done on this compound at this point, it’s not entirely clear what it is that causes this.

It could be the nutrient partitioning effects, or because of the increased nitrogen retention.

This is an important benefit. Typically, wetter compounds are going to help make the muscles pop better, but they are retaining a lot of water.

With LGD-3303, you don’t have that problem with water retention.

You get a quick boost in size and fullness, and you will have dry mass gains in the weeks that follow during your cycle.

You don’t have to worry about your muscular definition being hidden because of water retention.

#2. LGD 3303 Increases Strength

Next, it can provide some massive increases in strength.

You will notice that your strength gains are more pronounced when you are cycling with the compound.

The strength increase can last, as long as you are putting in the time and energy to keep those gains.

Of course, one of the first reasons the SARM was used was to help prevent muscle wasting.

This is still a benefit that athletes and bodybuilders will be able to enjoy.

#3. LGD 3303 Can Reduce Body Fat

The compound could also help to aid in fat loss, which can help you to appear even leaner and more muscular.

Having the ability to add muscle mass quickly while still retaining definition is one of the things that bodybuilders have always wanted.

In addition to lean muscle gains and muscle retention, there is some anecdotal evidence that it can help to strengthen the density of bones.

It can do all of this without putting too much strain on the body and organs. However, you do need to make sure you are taking it properly.

Because of the strength and mass gains, most people use it for those purposes.

However, it does have some versatility to it, and it could be used in cutting phases, as well.

As mentioned, this is considered one of the stronger SARMs on the market. It has the potential to be a good choice for your bodybuilding needs.

However, you should always buy carefully. Make sure you are getting the real deal.

Positive Reviews and Complaints About LGD-3303

Before you decide whether you should consider using LGD-3303, check out some reviews from others who have used the product.

Below are a couple of reviews from Reddit from people who have used the SARM.

You will find that the reviews are mostly positive, but they do come with some warnings about some potential problems that some users could face.

“I’m on 3303 right now, no test base and I probably won’t run a PCT either, never have run a Pct on SARMs either, as I find my body recovers really well naturally.

I’m 22 and have been training for 7 years now, never ran AAS but oh boy the pumps are incomparable to being 100% natural. I know how a good pump feels but this is on another level.

Strength is also through the roof, recovery between sets is also insane, even more insane than when I was on GW. Running 3303 solo, after I’ve finished my 1st month of 3303 only, I’m adding Mk677 for 2 months while having 1 month on 3303 left.

I recommend it, I get a little acne (very little) and very sensitive to heat but those are all the sides so far. So far worth it.”
Juztrandom (Reddit)

“I just ran it (LGD-3303) in a cycle with Dbol, which I used as my test base since I am unable to use needles in my current situation. Dbol @ 20mg a day, LGD 3303 @ 10mg a day for around 9 weeks.

For context, I’m pretty experienced with PEDs. I’ve run test, orals, and most SARMS (Osta, LGD, RAD), etc. I was in a pretty terrible place for the past few years, totally stopped working out.

I started up again about 6 months ago and ran this Dbol/3303 cycle to jumpstart my return progress. (I’m pretty much back to 100% strength now, muscle memory is awesome) It is some strong stuff.

I’m glad I used Dbol as hormone replacement because I’m positive running 3303 by itself would cause intense lethargy from the suppression. Compared to LGD 4033 and even RAD it’s significantly more intense.

Very dry and has insane effects on vascularity. It made my veins crazier than any other PED I’ve used.

Even being off of it for maybe 2 months there’s still a lasting effect which has never happened with any other compound in my experience.

“I gained about 15 pounds of lean muscle, but again that’s because of muscle memory, I just gained all of it back instead of creating it from scratch.

“If anyone IS interested in using it, I definitely would not do so without a test base of some kind. I however loved it and will probably use it in the future instead of methylated orals.”
Grandmaster_Zach (Reddit)

LGD-3303 vs. LGD-4033

A lot of people have been asking me about the differences (and similarities) between LGD3303 and LGD-4033.

Rather than go into a detailed written discussion, I recommend you watch the below video to learn more:

How To Take LGD 3303

Because there is relatively little research regarding LGD-3303, it can be difficult to know the correct dosage for your body.

Typically, you are going to want to be conservative with the dosage because this is considered one of the most powerful SARM options on the market.

For the most part, people are suggesting that you take a dose between 10 mg and 30 mg per day.

Again, because of the strength, it tends to be better to stay on the low end of things during your cycle.

One of the other important things to note is that LGD-3303 has a half-life of between six and 12 hours.

This means that you could take just a single dose per day, and as long as you are working out regularly, it will work.

You could also dose two times a day, which can ensure that it is constantly working on your muscles.

The cycle should also be short because this is an aggressive SARM.

You can start with a cycle of six weeks, take some time off the SARM and then do a second cycle a month or two later that is eight weeks long.

Where to Buy LGD 3303

As with other SARMs, you aren’t typically going to find these at your local GNC or grocery chain.

They are essentially research chemicals, but they are legal for you to buy and use.

However, this means you are going to be buying them online through various sellers.

Many companies claim to provide LGD-3303. However, many of them are selling low-quality products that aren’t the real deal.

If you’re looking for a safe, reliable, 3rd party tested, and true source for LGD-3303, look no further than Pure Rawz.

They sell a 30 ml bottle for just over $59, and have several different flavors available.

Click Here to see their page on LGD-3303.

Note: Pure Rawz also sells a tablet version, as well as a capsule version of LGD-3303.

See links to each below:

PCT After Taking LGD 3303

It’s recommended you take a PCT, such as Exemestane, after a LGD 3303 cycle.

The aggressive nature of the SARM also means you will need post cycle therapy (PCT) once you have finished your cycle.

This is done, so you can restore the hormones in your body.

Remember, the SARM is changing the way the hormones are working, and you need to make sure that those hormones get back to normal as quickly as possible.

It will help to ensure that your body starts to produce testosterone again in just a matter of weeks.

Failure to go through the therapy would be unhealthy for you, as it will take your body a lot longer to get the hormones back in balance.

It could take months or longer. During that time, you would experience symptoms of low testosterone, such as fatigue, decreased muscle mass, increased fat… a lot of the things you have been trying to avoid.

See a couple options for this below.

Aromatase Inhibitor

Something else you will want to take when you are using this SARM is an aromatase inhibitor.

The way LGD-3303 works is by binding tightly to the androgen receptors, which could cause increases in estrogen levels.

With the use of something like Arimistane, you can prevent this.

You could take 25 mg of Arimistane each day.

This is an aromatase inhibitor that can help to reduce some of the estrogen issues that you might have with the SARM otherwise.

We recommend that you cycle a product called Exemestane, which is available on the Pure Rawz official site here.

Another option would be a product called Anastrozole, which is also an effective aromatase inhibitor.

Click Here to visit the Pure Rawz page on that product.

Are There Side Effects of Taking LGD-3303?

Something else to note is that even though there are plenty of anecdotal accounts of these benefits, there hasn’t been as much research as some would like.

The benefits haven’t been evaluated by the FDA.

When evaluating the benefits of LGD-3303, it’s important to understand some of the potential negative effects of taking the compound.

Like other SARMs, you will find that there tend to be relatively few of these issues.

Still, this doesn’t mean that side effects are unheard of. Some potential issues have affected users.

It could worsen your lipid panel, cause severe testosterone depression, and it could be slightly liver toxic.6

This means you will want to take it the right way and with the right auxiliaries.


What do you think about trying LGD-3303? It has a lot of good buzz about it from bodybuilders because it can work so well.

It is potent, though, and it does require a lot of care to use it properly. It also means that you need to go through post-cycle therapy.

If you are looking for a powerful, aggressive SARM, though, it is going to be hard to beat.

With all of the above said, do your research when it comes to SARMS. 

They do have the ability cause some side effects in certain individuals, and should not be taken lightly.


  1. Dalton JT, Taylor RP, Mohler ML, Steiner MS. Selective androgen receptor modulators for the prevention and treatment of muscle wasting associated with cancer. Curr Opin Support Palliat Care. 2013;7(4):345-351. doi:10.1097/SPC.0000000000000015 (source)
  2. Solomon ZJ, Mirabal JR, Mazur DJ, Kohn TP, Lipshultz LI, Pastuszak AW. Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications. Sex Med Rev. 2019;7(1):84-94. doi:10.1016/j.sxmr.2018.09.006 (source)
  3. Vajda EG, López FJ, Rix P, et al. Pharmacokinetics and pharmacodynamics of LGD-3303 [9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo-[3,2-f]quinolin-7(6H)-one], an orally available nonsteroidal-selective androgen receptor modulator. J Pharmacol Exp Ther. 2009;328(2):663-670. doi:10.1124/jpet.108.146811 (source)
  4. Vajda EG, Hogue A, Griffiths KN, et al. Combination treatment with a selective androgen receptor modulator q(SARM) and a bisphosphonate has additive effects in osteopenic female rats. J Bone Miner Res. 2009;24(2):231-240. doi:10.1359/jbmr.081007 (source)
  5. National Center for Biotechnology Information. PubChem Compound Summary for CID 25195253. Accessed Mar. 4, 2022. (source)
  6. Cutler C, Viljanto M, Taylor P, Hincks P, Biddle S, Van Eenoo P. Identification of equine in vitro metabolites of seven non-steroidal selective androgen receptor modulators for doping control purposes. Drug Test Anal. 2022;14(2):349-370. doi:10.1002/dta.3189 (source)

See Also

Best SARMS For Bulking & Cutting

Best Supplement Stacks For Muscle Gain

ACP-105 Review

SR 9009 Review

Rob V.


4.5 out of 5 (29 Ratings)

LGD-3303 is a relatively new SARM that promises a number of benefits. Learn more about it in our exclusive review.
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