igf1-lr 3 melanotan 2 tb-500 dosage and how to take
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TB500, IGF-1 LR3, Melanotan 2: Dosage For Each

Peptides offer a ton of promise thanks to their anti-aging properties.

Furthermore, peptides are receiving more praise for their ability to influence weight loss and build lean muscle.

And, that’s not even the end of the potential benefits that peptides offer to men and women.

However, when starting any new supplement, people have questions about how to use peptides and the proper dosage.

Learn more about the suggested dosage for TB-500, IGF-1 LR3, and Melanotan 2:

TB-500 Dosage

tb500 dosage and how to take

Note: Click Here to pick up TB-500 from our #1 rated source, Core Peptides.

TB-500 is one of the most popular peptides currently available for sale online.

The peptide is a major game-changer when it comes to gaining lean muscle and resisting the signs of aging.1

TB-500 offers numerous health benefits including the ability to recover faster from wounds and injuries.2 3

But what is the recommended dosage for TB-500?

TB-500 is different from many other peptides in that proper storage and preparation are more important than the actual dosage.

Therefore, individuals who take the time and attention to prepare TB-500 correctly have the best chance at success.

TB-500 is typically packaged in a lyophilized powder form that must be reconstituted upon arrival.

Generally, the lyophilized powder is reconstituted with bacteriostatic water before it’s administered to the body.

Often, individuals have the choice of administering TB-500 via intravenous, intramuscular, or subcutaneous injection.4

It’s essential that the peptide is stored in a dry, cool, and dark location.

Then, after the reconstitution process is complete the peptide may be stored in a refrigerator to avoid any potential degradation.

In the past, it’s been reported that the effects of TB-500 take longer to work on some men and women compared to others.

Nevertheless, following the correct preparation and storage techniques goes a long way toward getting the results you want.

In the end, the amount of TB-500 you’ll want to administer depends on the pain level and/or severity of the injury.

For example, some sources suggest beginning with a low dosage (5 – 20mg p/ week) and monitoring the body for any changes or unwanted side effects.

Then, the dosage may gradually be increased yet administration should never occur more than 2 – 3x per week.

How to Use TB-500

TB-500 is completely dependent on the severity of an injury and how long it takes the body to recover from it.

As a result, TB-500 functions differently and sometimes the effects take shorter / longer depending on the individual.

Thus, the substance (like many other peptides) is very much trial and error until individuals find the threshold that meets their demands.

For this reason, you’ll find countless opinions on the best way to use TB-500 if you are looking to build lean muscle or avoid the signs of aging.

TB-500 peptide offers healing and pain relief through intramuscular or subcutaneous injections.5

Even better, the injection does not have to be at the site of the injury.

Rather, it’s suggested that the individual do whatever makes them the most comfortable or proves the most effective.

Often, it’s not a bad idea to cycle off peptides like TB-500 after using the substance for 4 – 6 weeks.

Additionally, many bodybuilders approach TB-500 differently by establishing their own dosage and supplement routines.

The goal of this approach is to avoid injury, recover faster from intense workouts, and ultimately pack on more lean muscle.

Be that as it may, there is no single precise or exact method for taking TB-500.

For example, some individuals prefer to “load” the peptide with a higher dose for the first 4 – 6 weeks before dropping down to a lower / “maintenance” dose.

In the end, people should do what they consider best for themselves and consult a physician with any questions or concerns.

It’s impossible to predict how peptides will interact with other prescribed medications or preexisting conditions.

Therefore, beginners usually start with a low dosage and gradually build up tolerance in the body before introducing more of the peptide.

IGF-1 LR3 Dosage

igf1-lr3 peptide dosage and how to take

Note: Click Here to pick up IGF 1 LR3 from our #1 rated source, Core Peptides.

Insulin-like Growth Factor (IGF-1) is a natural hormone found within the body that aligns closely with the production of human growth hormone (HGH).6

For this reason, IGF-1 LR3 has transformed into a popular peptide for producing lean muscle and losing weight.

The lengthened version of traditional IGF-1 possesses 13 additional amino acids and is known to significantly increase muscle mass.7

As a result, it’s easy to determine why this peptide has become so popular with athletes, bodybuilders, and those seeking to slow down aging.

However, it’s important to follow a precise dosage and injection routine with IGF-1 LR3, unlike TB-500.

Therefore, new users should begin with a lower dosage before eventually climbing to 20 – 40 mcg per day.8

It’s not necessary to administer IGF-1 LR3 more than 2 – 3x per week and supplement cycles should not last longer than 4 – 6 weeks.

Furthermore, users should never attempt to exceed 100 mcg per day to avoid harmful side effects.

Often, individuals choose to Post Cycle Therapy (PCT) off powerful peptides and supplements like IGF-1 LR3.

Therefore, some experts suggest turning to a SERM (Tamoxifen, Clomid) for PCT which usually lasts 2 – 3 weeks following the end of a cycle.9

In general, those seeking to gain lean muscle and build mass rely on “weight stacking” to achieve better results.

As such, IGF-1 LR3 is often paired with other peptides and SARMs for even stronger results at the gym.

How to Use

IGF-1 LR3 is usually administered via subcutaneous injection 1 – 2x per day.

There are many experts who suggest the best time to inject IGF-1 LR3 is once in the morning.

Then, the second dosage should be applied post-workout.

Doing so will ensure that users maximize peak times for IGF-1 while also providing the means for sufficient rest and recovery.

Furthermore, men and women can increase their chances of success by following a high protein, moderately carb-restricted, caloric surplus diet.

The correct diet and workout regime are just as important to gaining lean muscle as anything else so make sure not to skip out on this step.

Regardless, injecting IGF-1 LR3 offers the ability to significantly improve muscle mass and lose weight.

You can buy IGF-1 LR3 from our #1 recommended source, Core Peptides. 

Click Here to visit their page on it.

Melanotan 2 Dosage

melanotan-2 peptide dosage and how to take

Note: Click Here to pick up Melanotan 2 from our #1 rated source, Paradigm Peptides. (Core Peptides no longer carries Melanotan 2)

Melanotan 2 features many benefits including healthy skin and better pigmentation.10

Additionally, the peptide is linked to improved appetite and energy levels.11

Furthermore, many men insist that Melanotan 2 also improves sexual arousal.12

The recommended dosage for Melanotan 2 varies from 0.01mg – 0.5mg per day.

Unfortunately, there is no precise recommended dosage because Melanotan 2 is not yet approved by the FDA.

Consequently, many who use peptides rely on some trial and error before they discover the magic formula for their body.

Notwithstanding, beginners should always start on the lower end of the spectrum and gradually work their way up to a higher dosage.

How to Use

Melanotan 2 is produced in a lyophilized powder form just like many other peptides (i.e. TB-500).

Consequently, the power must also be reconstituted with bacteriostatic water before use.

The good news is that most suppliers usually provide a vial with the shipment that is designed to mix the powder substance with sterile water.

Next, the ingredients are combined in the vial, mixed, and stored in a refrigerator overnight or until the powder completely dissolves.

It’s okay to swirl or tilt the vial but make sure it’s never shaken during the reconstitution process.

Then, after the peptide is reconstituted it’s also crucial to follow proper storage techniques (cool, dark, dry room).

In the past, it’s been reported that many users prefer to use the peptide before nighttime activities, such as the desire to have sex.

Melanotan 2 has demonstrated rapid results especially when injected directly into the bloodstream.

Thus, many men prefer to administer Melanotan 2 immediately after dinner yet before bedtime.

Check out our complete Melantonan 2 review here.


It’s important that new users follow the recommended dosage for any new peptide or supplement.

However, the directions are not always extremely clear and decisive in terms of dosage or proper use.

In the past, many users have experimented with peptides like TB-500 and IGF-1 LR3 until they achieved desirable results.

Therefore, start low and slow and monitor how the body responds to any new substance before progressing to higher doses.

More importantly, only rely on proven and trustworthy suppliers like Core Peptides.


  1. Maar K, Hetenyi R, Maar S, et al. Utilizing Developmentally Essential Secreted Peptides Such as Thymosin Beta-4 to Remind the Adult Organs of Their Embryonic State-New Directions in Anti-Aging Regenerative Therapies. Cells. 2021;10(6):1343. Published 2021 May 28. doi:10.3390/cells10061343 (source)
  2. Treadwell T, Kleinman HK, Crockford D, Hardy MA, Guarnera GT, Goldstein AL. The regenerative peptide thymosin β4 accelerates the rate of dermal healing in preclinical animal models and in patients. Ann N Y Acad Sci. 2012;1270:37-44. doi:10.1111/j.1749-6632.2012.06717.x (source)
  3. Malinda KM, Sidhu GS, Mani H, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364-368. doi:10.1046/j.1523-1747.1999.00708.x (source)
  4. Xiong Y, Mahmood A, Meng Y, et al. Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury. Ann N Y Acad Sci. 2012;1270:51-58. doi:10.1111/j.1749-6632.2012.06683.x (source)
  5. Pingali U, Nutalapati C, Koilagundla N, Taduri G. A randomized, double-blind, positive-controlled, prospective, dose-response clinical study to evaluate the efficacy and tolerability of an aqueous extract of Terminalia bellerica in lowering uric acid and creatinine levels in chronic kidney disease subjects with hyperuricemia. BMC Complement Med Ther. 2020;20(1):281. Published 2020 Sep 15. doi:10.1186/s12906-020-03071-7 (source)
  6. Assefa B, Mahmoud AM, Pfeiffer AFH, Birkenfeld AL, Spranger J, Arafat AM. Insulin-Like Growth Factor (IGF) Binding Protein-2, Independently of IGF-1, Induces GLUT-4 Translocation and Glucose Uptake in 3T3-L1 Adipocytes. Oxid Med Cell Longev. 2017;2017:3035184. doi:10.1155/2017/3035184 (source)
  7. Philippou A, Barton ER. Optimizing IGF-I for skeletal muscle therapeutics. Growth Horm IGF Res. 2014;24(5):157-163. doi:10.1016/j.ghir.2014.06.003 (source)
  8. Tomas FM, Chandler CS, Coyle P, Bourgeois CS, Burgoyne JL, Rofe AM. Effects of insulin and insulin-like growth factors on protein and energy metabolism in tumour-bearing rats. Biochem J. 1994;301 ( Pt 3)(Pt 3):769-775. doi:10.1042/bj3010769 (source)
  9. An KC. Selective Estrogen Receptor Modulators. Asian Spine J. 2016;10(4):787-791. doi:10.4184/asj.2016.10.4.787 (source)
  10. Gilhooley E, Daly S, McKenna D. Melanotan II User Experience: A Qualitative Study of Online Discussion Forums. Dermatology. 2021;237(6):995-999. doi:10.1159/000514492 (source)
  11. Côté I, Sakarya Y, Kirichenko N, et al. Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction. Can J Physiol Pharmacol. 2017;95(2):206-214. doi:10.1139/cjpp-2016-0290 (source)
  12. Wessells H, Levine N, Hadley ME, Dorr R, Hruby V. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000;12 Suppl 4:S74-S79. doi:10.1038/sj.ijir.3900582 (source)

See Also

Best Places To Buy AOD 9604, TB-500, And Sermorelin

Best Places To Buy CJC-1295, PT-141, & Ipamorelin

Best Peptides For Weight Loss & Fat Burning

5 Best Peptide Sources / Companies

Ipamorelin Peptide Review

Rob V.
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