Tesofensine is a wonderful mistake that transformed into a blessing.
The peptide was originally developed for the treatment of Alzheimer’s Disease and Parkinson’s.
However, a 2006 breakthrough discovered that Tesofensine is much more productive at helping people lose weight.
Furthermore, the ability to suppress appetite and cravings assists individuals with keeping the weight off.
Learn more about the 8 exciting benefits of Tesofensine:
Table of Contents
Tesofensine Peptide: 8 Major Benefits
Note: Click Here to pick up Tesofensine from our #1 rated source, Pure Rawz.
Sometimes, mistakes are blessings in disguise.
The peptide Tesofensine is a classic example.
Tesofensine was first developed and observed as an experimental treatment for Parkinson’s Disease (PD) and Alzheimer’s Disease (AD).
However, in the early 2000s, it was discovered through various studies that Tesofensine is far more effective at weight loss.
Since then, the serotonin-noradrenaline-dopamine reuptake inhibitor (SNDRI) has witnessed multiple breakthroughs.1
Accordingly, researchers have found several noteworthy benefits:
- Weight Loss
- Reduces Hunger Cravings
- Improves Metabolism
- Cognitive Health Benefits
- Addiction / Mental Health
- Improves Energy & Mood
- Type II Diabetes Treatment
- Sexual Dysfunction
Tesofensine is a type of peptide classified as a triple reuptake inhibitor (TRI).2
In other words, these substances are known to improve mood, focus, and energy.
Thus, it should come as no surprise that the National Institute of Health (NIH) has labeled TRIs “the next generation of antidepressants.”3
Discover 8 important benefits of Tesofensine, below:
#1. Weight Loss
Tragically, the United States just gets more and more obese.
In fact, it’s estimated that by 2030 nearly half of the U.S. population will be overweight with 25% considered “severely obese.”
Unfortunately, the weight loss diets and workout plans of the past have failed individuals desperate to lose weight.
The good news is that discoveries are being made every day, one of which is the revolutionary weight loss peptide Tesofensine.4
Tesofensine is unique in that it was discovered accidentally yet ironically produces better results than supplements designed for that purpose.
Nevertheless, the scientific breakthrough has enabled researchers to more closely examine this powerful peptide for its ability to suppress appetite.
Tesofensine has been examined in multiple studies, including a 2008 placebo-controlled clinical trial that included more than 150 participants.5
In the end, the results were astonishing as Tesofensine was more than twice as effective as comparable weight loss supplements.
Even better, the participants in the clinical trial were able to burn the excess fat without substantial lifestyle changes (diet, exercise, etc).
Tesofensine 2x More Effective Compared to Weight Loss Diets
According to Dr. Arne Astrup, the findings can help close the “enormous gap between existing weight loss compounds and gastric surgery.”
In fact, Dr. Astrup believes that individuals can lose as much as 20% of the extra weight they would during gastric surgery.
Medical experts attribute this groundbreaking discovery to accelerated fat oxidation along with increases in dopamine levels.6
Dopamine is effective at regulating appetite and reducing hunger cravings (see, below).7
Moreover, the “feel-good hormone” has a tremendous impact on mood and motivation, among other factors.
It’s known to improve metabolism (more details, below) by increasing thermogenesis.8
Meanwhile, dopamine deficiency can actually lead to individuals gaining weight, among other health problems.9
Therefore, it’s easy to understand the importance of optimal dopamine and serotonin levels in regards to weight loss.10
And, other countries are beginning to take notice as Tesofensine has recently entered phase III clinical trials.
#2. Reduces Hunger Cravings
The reality is there is no point in taking the time and effort to lose weight only to have it gradually return.
Thus, a huge aspect of weight loss is the ability to reduce the desire for food and late-night cravings.
Unfortunately, previous weight loss programs have failed in that regard as most attempt to starve the individual.
Nevertheless, Tesofensine produces effective weight loss while also suppressing appetite.
For this reason, most men and women who use Tesofensine report:
- Substantial weight loss
- Increased energy metabolism
- Limited hunger cravings
- Improved body composition
The ability of Tesofensine to reduce hunger cravings has been verified in a 2012 study conducted on animals as well as experiments on humans.11 12
Researchers summarize that the peptide suppresses appetite by influencing the lower striatal dopamine D2 receptor (D2/3R).13
Furthermore, studies have concluded that Tesofensine can assist with binge eating disorders usually caused by stress or depression.14
#3. Improves Metabolism
Losing weight is critical but only if the individual is capable of keeping the extra pounds off the body.
Therefore, having the ability to control hunger cravings and improve metabolism is also required for any dependable weight loss product.
Fortunately, Tesofensine improves metabolism by spurring a process known as thermogenesis.
According to the NIH, early adaptive thermogenesis is crucial to burning fat and keeping it away.15
Generally, metabolism is better in your hunger years and gradually loses its effect.
Thus, finding supplements that also improve metabolism is just as important as what you invest in a diet or workout program.
In fact, Tesofesine has proven effective without the need to significantly alter diet or exercise from your normal routine.
Most experts attribute this effect to how Testofesine accelerates thermogenesis and therefore restores metabolism.
As a result, the combination of reduced cravings, increased dopamine, and thermogenesis leads to a complete body overhaul.
#4. Cognitive Health Benefits
It’s important to recall that Tesofensine was first developed to treat neurodegenerative disorders like Parkinson’s and Alzheimer’s Disease.
However, those needs quickly took a backseat after the rapid weight loss effects were discovered.
Be that as it may, there is still hope that Tesofensine offers cognitive health benefits despite the early research failures.
Researchers believe that the peptide preserves cognitive health by influencing cholinergic neurotransmissions.16
Cholinergic neurotransmissions represent a process where nerve cells relay messages to each other.
Unfortunately, these nerve cells can get damaged or struggle to relay messages due to a variety of factors.
Even worse, multiple studies demonstrate that obesity serves as a major risk factor for cognitive impairment, especially in the older population.
Therefore, the ability of the peptide to increase brain-derived neurotrophic factor (BDNF) production goes a long way in reversing this struggle.17
Consequently, studies have revealed that Tesofensine can improve memory, problem-solving skills, and learning abilities.
#5. Addiction & Mental Health
According to the NSDUH, nearly 20 million American adults have a substance use disorder.
And, by far the most significant substance use disorder is alcohol abuse.18
Neurotransmitters play a tremendous role in alcohol addiction.19
Alcohol is known to affect neurotransmitter systems in the brain leading to addictive, self-destructive habits.
Despite it, there is the promise and hope for a better future thanks to peptides like Tesofensine.
The peptide is associated with alcohol addiction because it has the potential to repair neurotransmitters as well as increase dopamine levels.
For this reason, some experts believe it has a future helping cure men and women from substance abuse disorders like alcoholism.
Triple reuptake inhibitors (TRIs) have been linked to reducing alcohol consumption because they limit the risk-reward behaviors of substance abuse.20
Furthermore, the anti-depressant properties of TRIs gradually lead to less reliance on dangerous substances to achieve that same reward.
Be that as it may, more clinical research is necessary to reach a firm conclusion on how Tesofensine treats substance abuse.
Nevertheless, those who cannot risk spending another day addicted may feel like the unknowns with Tesofensine are worth it.
#6. Improves Energy & Mood
It’s been examined that Tesofensine increases the transmission of 3 critical neurotransmitters in the brain:
- Dopamine
- Serotonin
- Norepinephrine
These neurotransmitters regulate energy and mood and affect your weight for better or worse.21
As such, it’s imperative that men and women focus on keeping these neurotransmitters at optimal levels.
Tesofensine indirectly improves mood and energy thanks to increases in dopamine and serotonin.
These compounds are imperative to feeling motivated and driven, as well as having happiness and satisfaction in life.
Unfortunately, being overweight does the opposite, not only reducing energy but leaving the individual feeling sad and disgruntled with their image.
Thankfully, peptides like Tesofensine also improve BDNF production which goes a long way toward improving mood and energy.22
#7. Type II Diabetes Treatment
Diabetes is another significant health problem and one of the most devastating preventable diseases.
Type II diabetes produces many unwanted side effects and currently has no cure.23
Notwithstanding, some peptides like Tesofesine have accomplished major strides in helping bring relief.
For starters, Teosfensine has a beneficial effect on blood sugar.
Therefore, by promoting weight loss, the peptide may indirectly improve insulin sensitivity in overweight individuals.
Insulin sensitivity refers to the ability of the body to respond to the effects of insulin.24
Thus, any hormone that can allow glucose (blood sugar) from the bloodstream to enter and be utilized by cells for energy production improves symptoms.
More importantly, losing weight goes a long way toward improving the conditions of type II diabetes.
In the past, clinical trials have revealed that Tesofensine improves blood sugar levels, even in obese patients.
#8. Sexual Dysfunction
Sexual dysfunction is a severe problem that is affecting more and more men, even at a younger age.
It contributes to serious, life-altering issues like erectile dysfunction (ED).25
And, while research is still limited, there are indications that Tesofesine can also improve sexual dysfunction.
The antidepressant properties of the peptide are known to improve energy and mood, which also has a direct impact on men’s sex lives.
Accordingly, the ability to improve dopamine levels and other crucial neurotransmitters also rewards men in the bedroom.
There are customer reviews and testimonials regarding how peptides improve the quality of sex and erections.
Perhaps in the future with more research dedicated to the subject, more groundbreaking results will also appear.
For now, most users of Tesofesine report better sleep quality along with more enjoyable sex.
It could be a direct result of the enhanced neurotransmitters, or a byproduct of improved confidence and quality of life.
Regardless, your partner will not complain thanks to the improved sexual performance.
Tesofesine Peptide: Where To Buy?
Are you looking to buy high-quality Tesofensine?
Customers should look no further than PureRawz Peptides.
PureRawz features the latest in top-rated peptides and nootropics, click here to see their page on Tesofensine.
The premium compounds are tested for purity at a minimum purity of 98%.
Furthermore, PureRawz insists on having all of its products third-party confirmed for quality control.
Thus, you can ensure you are getting the best with PureRawz.
The company offers fast, reliable, free shipping on all orders over $100.
Customers with questions or concerns should not hesitate to contact their phenomenal online support, available 24/7.
Conclusion
The primary benefits of Tesofensine were discovered by accident.
The peptide was originally developed as treatment for Alzheimer’s and Parkinson’s Disease.
However, discoveries in the early 2000s led to a monumental weight loss breakthrough.
Today, the peptide is mostly used by individuals seeking to lose weight and control hunger cravings.
It also features many other potential benefits that require more research before experts can reach a firm conclusion on the peptide.
References
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- van de Giessen E, de Bruin K, la Fleur SE, van den Brink W, Booij J. Triple monoamine inhibitor tesofensine decreases food intake, body weight, and striatal dopamine D2/D3 receptor availability in diet-induced obese rats. Eur Neuropsychopharmacol. 2012 Apr;22(4):290-9. doi: 10.1016/j.euroneuro.2011.07.015. Epub 2011 Sep 1. PMID: 21889317. (source)
- Gilbert JA, Gasteyger C, Raben A, Meier DH, Astrup A, Sjödin A. The effect of tesofensine on appetite sensations. Obesity (Silver Spring). 2012 Mar;20(3):553-61. doi: 10.1038/oby.2011.197. Epub 2011 Jun 30. PMID: 21720440. (source)
- de Weijer BA, van de Giessen E, van Amelsvoort TA, Boot E, Braak B, Janssen IM, van de Laar A, Fliers E, Serlie MJ, Booij J. Lower striatal dopamine D2/3 receptor availability in obese compared with non-obese subjects. EJNMMI Res. 2011 Dec 16;1(1):37. doi: 10.1186/2191-219X-1-37. PMID: 22214469; PMCID: PMC3265412. (source)
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