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LGD-4033 Review: Ligandrol Benefits, Results, Side Effects, & More

Struggling to build muscle mass? You’re not alone. Millions of people in the US find that achieving critical gains is more challenging than they had anticipated.

Some even find that their own bodies fight against their efforts to bulk up.

One potential solution is to use SARMs – selective androgen receptor modulators – like Ligandrol (LGD-4033).

What is this drug and how does it work? We’ll break down everything you need to know in this review.

NOTE: The below supplements are NOT intended for those under the age of 18.  If you are under the age of 18, do NOT consider taking them under any circumstances whatsoever.

Also, if you’re planning on joining the military, cease using this (and really any) supplement at least a couple months before going to MEPS. 

They can cause a false positive on a drug test, and will affect your chances of joining!

What Is Ligandrol (LGD-4033)?

does ligandrol lgd-4033 really work

Note: Click Here to buy LGD-4033 legally online from our #1 rated source, Pure Rawz.

Ligandrol (LGD-4033) is a selective androgen receptor modulator, or SARM.

It’s part of a growing class of research chemicals being investigated for their use in treating muscle wasting and weakness.

These conditions are often associated with the aging process but can also affect those struggling with illnesses, especially those that leave them bedbound.

It’s also important to note that LGD-4033 is prohibited under class S1.2 Other Anabolic Agents on the WADA Prohibited List and is prohibited from use by all athletes at any level, from professional to recreational use.1

It has also been associated with serious side effects, including liver damage, heart attack, and stroke among the more serious ones.2

What Benefits Does LGD-4033 (Ligandrol) Claim?

Like other SARMs, LGD-4033 has been shown to increase lean muscle mass in the body.

The pharmaceutical is designed to deliver the benefits of a testosterone supplement, but with improved safety and patient acceptance.

It also creates significant anabolic activity in bones, potentially helping to strengthen them.

Some of the most impressive claims of Ligandrol include the following:

  • Potential treatment for muscle wasting
  • Potential treatment for osteoporosis by increasing bone density and preventing loss
  • Potential use for building lean muscle mass
  • Potential use for maintaining lean muscle mass even with a reduced caloric intake

In addition, LGD-4033 offers several advantages over anabolic steroids, which have been the traditional solution for bodybuilders struggling to bulk rapidly.

For instance, because this SARM is highly targeted at muscles and bones, it doesn’t have the same range of side effects on other parts of the body.

It also does not convert on estrogens or DHT, cause gynecomastia, or lead to the retention of water and salt in the body. It is also not linked to:

  • Hair loss
  • Facial swelling
  • Acne/oily skin
  • Behavioral changes
  • Sleeping difficulties
  • Short-term aggression and violence

The side effects above are primarily associated with traditional anabolic steroids.

Side Effects of LGD-4033 (Ligandrol)

As you can see from our list above, Ligandrol (LGD-4033) offers a wide range of benefits.

However, it’s important to consider both sides of the coin when deciding whether to take a research chemical that has the potential to affect your body.

While LGD-4033 does have its benefits, there are also some pretty significant potential side effects associated with taking it.

Below, we’ve broken these up into minor and major side effects so you can make a more informed purchase decision.

We’ve also included a list of side effects that you might experience should you stack this with other SARMs (which is a common practice to achieve heightened benefits).

Potential Minor Side Effects of LGD-4033 (Ligandrol)

  • Headache
  • Dry mouth
  • Reduced testosterone at higher dosages

Potential Major Side Effects of LGD-4033 (Ligandrol)

  • Increased risk of heart attack
  • Increased risk of adverse effect on blood lipid levels
  • Increased risk of stroke
  • Increased risk of liver damage
  • Decreased HDL cholesterol (good cholesterol)

Note that the side effects of stacking are generally related to low testosterone.

It’s also important to note that this product is not approved for human use by any nation.

Users should also understand that the long-term effects have not been established, and that there may be additional side effects that occur with usage over time.

LGD-4033 and Sports

All levels of professional and amateur sports test for LGD-4033 and other SARMs.

The World Anti-Doping Agency has added Ligandrol to its list of banned substances.3

Many top athletes around the world have tested positive for this SARM and have been banned from competing for that reason.

In most cases, urine tests are conducted to check for LGD-4033 metabolites.

Australian swimmer Shayna Jack was banned from competing for two full years for testing positive for LGD-4033, although she denied actively taking the drug and suggested that it had been a contaminant in another supplement.4

How Does Ligandrol Work?

Unlike anabolic steroids, which often must be injected into the body, Ligandrol is taken as an oral liquid.

In most cases, this is a liquid that can be dripped onto the tongue, or added to a beverage if preferred.

Its performance in the body is very similar to other SARMs, and is as follows:

  • The pharmaceutical binds to specific androgen receptors in the body’s muscles and bones.
  • Once bound, the drug ignites a cascade of processes that change the expression of various genes within the DNA of the body’s muscle and bone cells.
  • These changes accelerate the repair rate of the cells, particularly muscle cells. They also accelerate cellular growth.
  • The result is faster muscle growth, the ability to maintain muscle growth even while cutting calories (such as during “cutting”), and better bone strength and regeneration.

Let’s put this in another way. SARMs and traditional steroids achieve similar results.

Both of them help you build muscle mass. And because muscle tissue requires more calories to support it, you can burn fat very quickly.

The result? A cut, bulked physique, and the ability to burn fat even in your “problem areas.”

What You Can Expect From Taking LGD-4033

Many people who take SARMs, and Ligandrol in particular, do so not just for the increased lean muscle mass and boost to their strength, but for increased vascularity and muscle hardening.

Here’s a few of the primary benefits you can expect from taking Ligandrol:


There’s a certain look to the physique of the world’s top bodybuilders. They’re not just burly. They’re cut, clean, and their veins positively bulge.

Ligandrol is recognized as one of the best SARMs for improving vascularity.

It’s not just about looks, though. Bigger veins mean better blood and oxygen transportation throughout the body, which improves endurance.

That means you’ll be able to beat old PRs and set new ones regularly!

Muscle Hardening

To get lean, hard muscle, you used to have to focus on endurance workouts.

Otherwise, you might get bulk, but the tissue would be relatively soft.

Of course, endurance work tends to create flatter, leaner (less bulky) muscle, which isn’t all that impressive visibly.

So, you might have rock-hard muscles, but because you focused on endurance work, you’re long and lean, rather than ripped.

With a Ligandrol, you can achieve muscle hardening by focusing on bulk work rather than endurance-centric exercises.

Increased Strength

Building muscle does not always equate to strength gains.

Look at some of the world’s top body builders and you’ll find that while they can lift a lot of weight once, they cannot do it multiple times.

They lack stamina (endurance) and true strength.

However, there is anecdotal evidence from recreational users of LGD-4033 that it enables true strength gains with just a few usage cycles.

What does that mean for you, though? Some users have reported gains of as much as 35% in strength from one or two cycles.

Of course, your results may vary and will be based on a wide range of personal factors.

However, you can expect increased strength, improved fat burning, and decreased recovery times.

LGD-4033 Ingredients

SARMs like Ligandrol usually do not contain traditional ingredients found in natural supplements, although specific product formulations may combine SARMs with other ingredients recognized for their potential in performance enhancement.

LGD-4033 is a research chemical and was designed in a laboratory.

The technical name for this drug is 4-((R)-2-((R)-2,2,2-Trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-(trifluoromethyl)benzonitrile.5

Ligandrol Positive Reviews and Complaints

The reviews of LGD-4033 are primarily positive, with an average star rating of 4.8 stars.

Men (and some women) have reported gaining considerable lean muscle mass in a relatively short time, increasing their ability to bulk and burn fat, their vein visibility, and their muscle hardness.

Here’s just a few that we came across: 

Definitely legit stuff. Saw all the effects I was expecting right off the bat. No indication that this was anything more or less than pure LGD4, which makes me feel secure. Love y’all’s stuff!
– Max S.

I got both rad140 and lgd4033 to stack and results are insane. The order time is pretty fast too. I’ve also had good customer service with any issues for the most part.
– Benny P.

Great stuff noticed significant gains in the first few weeks and really changed my life. I’ve struggled with bulking up for a long time. Can’t wait to get my next package!
– Brandon M.

In addition, I recommend you check out Greg Doucette’s video on Ligandrol below, it’s very informative:  

However, it’s important to remember that the long-term effects of Ligandrol are not well documented.

There is also the potential for significant side effects during the short term.

At least one person suffered a liver injury during a clinical trial of LGD-4033, although it was not clear that the injury was directly related to the drug.

However, the hepatotoxicity was consistent with these types of pharmaceuticals.

How to Use LGD-4033 (Ligandrol)

Taking Ligandrol is a relatively simple process. You only need to take 10mg per day.

You can do this by dripping directly on the tongue, or by adding a few drops to your preferred beverage.

For example, Pure Rawz sells a 30 ml bottle which contains a dropper that holds 1 ml per full drop.

Many bodybuilders also prefer to stack LGD-4033 with other SARMs and other natural supplements to get even more benefits.

One of the most common stacks is a combo of Ligandrol with S4 (or Andarine) along with MK-677 (or Ibutamoren).

Click Here to check out this popular stack on the Pure Rawz website.

What sorts of results might you see with a beginner’s dosage?

Most people gain between 10 and 15 pounds of muscle mass. It should take between eight and 12 weeks to achieve.

However, note that many people report water retention during this time, so your results may not be pure muscle mass.

Once you’ve gotten acclimated to the 10mg dose and plateaued, you can step up to the next level, which would be 15mg per day.

You’ll want to remain here until your results plateau once more, and then you can move up to the advanced dosage of 20mg per day.

Note that the most common recreational dosage for men is between 10 and 20mg per day.

Women usually take less, and the most common recreational dosage is between five and 10mg per day.

However, you can see results from dosages as low as 0.1mg per day.

Cycling LGD-4033 (Ligandrol)

Taking SARMs like Ligandrol can yield significant results.

However, it does depress your body’s ability to produce testosterone.

The side effects of long-term low testosterone can be considerable, so it’s recommended that you cycle correctly.

You’ll want to create an on and off schedule that gives your body time to ramp up testosterone production once more.

Many people follow a basic schedule that looks like this:

  • Weeks 1 through 8: Take your standard dosage of LGD-4033 every day.
  • Weeks 9 through 12: Take your standard dosage of LGD-4033, as well as PCT.
  • Weeks 13 through 20: Stop taking LGD-4033 and PCT and allow your body to naturally recover.

What happens if you fail to take time off from LGD-4033?

Your testosterone levels will remain depressed.

That can lead to some of the side effects we discussed earlier, such as reduced libido, headaches, nausea, and even muscle loss and other physical challenges.

Where to Buy Ligandrol (LGD-4033)?

You can buy Ligandrol online through several different retailers. However, there’s one in particular thats stand out from the crowd: Pure Rawz

Pure Rawz has been a leading SARMS source for years, and you’ll find a wide range of high-quality products to help you boost your performance.

Click Here to visit their page on LGD-4033 liquid version.

Addiationally, Pure Rawz offers several other variations of LGD-4033, including capsules, tablets, powder, and injectables.

Here’s links to each: 


Should you buy LGD-4033? That is a very personal question and one that only you can answer.

This SARM offers a proven ability to build lean muscle mass, preserve muscle mass during your cutting efforts, and even strengthen bones.

However, there are also serious potential side effects to consider, including an increased risk of stroke, heart attack, and liver damage.

If you compete on any level, understand that this drug is banned and if testing reveals it in your system, you run the risk of being prevented from competing for years at a time.

This is why we don’t recommend consumption by professional, or even semi-professional athletes.

Like all other SARMs, Ligandrol is not approved for use in humans by any government or government agency in the world, although it is legal to buy and sell it as an experimental substance.

With that said, there is no denying that LGD-4033 has some serious potential benefits, if taken correctly.

References / Resources


See Also

Best SARMS For Bulking & Cutting

MK-677 (Ibutamoren) Review

MK-2866 (Ostarine) Review

RAD-140 (Testolone) Review

Best Supplement Stacks For Muscle Gain

Rob V.


4.8 out of 5 (51 Ratings)

Does Ligandrol really work? Our LGD-4033 review discusses everything you need to know, from user testimonials, how to take it, what the benefits are, and more.
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